The autumn aura confronts us with the passing of time. The funeral of Queen Elizabeth II has become a symbol of transition for all of us, uniting billions of people around the world in reflection and wistfulness. Changes and integration have been topics that psychiatry and psychotherapy have been facing for centuries. Ability to deal with suffering and pain, illness and loss, but also to be open to changes and novelty, to search for hope and renovation. In our autumn issue of APP, we encourage you to familiarize yourself with the set of as always interesting and innovative publications, in which the authors try to take on these challenges. Sylwia Michałowska discusses essential and sensitive topic of sexual satisfaction, relationship satisfaction, and body image in patients with BRCA mutation after prophylactic mastectomy and/or adnexectomy. She shows that there are relationships between body assessment and sexual satisfaction as well as between body assessment and relationship satisfaction, and that there are differences in these areas between the groups of women who performed preventive mastectomy, adnexectomy, both procedures or non.